Both westbound lanes of Interstate 10 near Exit 50 were shut down after an elderly man driving the wrong way crashed into another vehicle, a Mississippi Highway Patrol official said Sunday evening.
MHP Cpl. Chase Elkins said it appeared the man was traveling eastbound in the westbound lanes when his truck hit a car just west of the 50-mile marker at about 6 p.m.
The driver of the truck, a 2016 Dodge Ram, was a 78-year-old man from Cerritas, California, Elkins said.
The truck crashed head-on into a 1989 Toyota Camry, and the driver and passenger were pronounced dead at the scene.
The California man was taken to a hospital for treatment of minor injuries.
All three people were wearing seat belts, Elkins said.
Traffic was diverted onto Mississippi 609 while the roadway was cleared.
The names of the two people killed in the crash have not yet been released.