Southern Miss defensive line coach Derrick LeBlanc was let go on Sunday, Thayer Evans of Sports Illustrated reports.
LeBlanc served on the USM staff in both of Todd Monken's two years as head coach.
USM (3-9) struggled on defense against the run this season, giving up 216.3 yards per game to rank 109th in nation.
LeBlanc worked as the defensive line coach for one season at Wyoming before he joined the USM staff. He was also the defensive line coach at Missouri State from 2006-07.
The USM defense was embarrassed in Saturday's season-ending 45-24 loss to UAB. The Golden Eagles gave up 371 yards rushing, including a UAB record 267 yards to Jordan Howard.