The Double-A Biloxi Shuckers will host their parent club, the Milwaukee Brewers, in a 1:10 p.m. exhibition game April 2 at MGM Park.
The Brewers are coming off a 68-94 season in 2015, which included the hiring of Craig Counsell as the team's new manager May 4.
Perennial all-star outfielder Ryan Braun and power-hitting first baseman Adam Lind highlight the Brewers roster entering the offseason.
This will mark the first time the Coast has hosted a major league team since 1935, when the Washington Senators held spring training in Biloxi. They played their games at Biloxi Stadium, which is now Keesler Air Force Base.
"We appreciate all of the work that (president) Ken Young, (general manager) Buck Rogers and the entire Shuckers staff do to provide a first-class home for our Double A club," Brewers general manager David Stearns said in a press release. "MGM Park is a state-of-the-art facility and 2015 was a terrific first season there with the team advancing to the Southern League Championship. We look forward to the major league club visiting next year and to many more seasons of a great partnership between our organizations."
It's not unusual for an MLB team to visit one of its farm clubs during the spring, but it's not something that happens every year.
"This is my 20th year in minor league baseball and we've never had the major league club come to town," Rogers said. "It will be a great experience for the fans. I'm pretty excited about this.
"This gives you an indication of how the Brewers are dedicated to the Gulf Coast by committing to this. They could leave spring training and go straight to Milwaukee, but they're coming to the Coast. It's a way for the Brewers to reward fans for their loyalty."
The exhibition game will mark the end of the Brewers' spring training. Opening Day will be April 4 in Milwaukee against the San Francisco Giants.
The Brewers conduct spring training in Phoenix, which means Biloxi an out-of-the-way jaunt.
The only way to be guaranteed tickets to the exhibition game is to be a Shuckers season-ticket holder.
Season-ticket holders will be able to buy tickets to the game before sales open to the general public.
Starting in December, tickets will go on sale to non-season ticket holders.
Tickets for club-level seating will be $45. Box-level tickets are $40, reserved-level tickets are $35 and berm/standing-room tickets are $25.
The Shuckers open the season April 7 with a seven-game homestand.