When it comes to people-moving on the Mississippi Coast, think linear - east/west linear. Yes, there is land to the north and some pretty nice roads to get you there, but it won't lead you to all things entertainment.
Beach Boulevard - some stodgy folks may call it U.S. 90 - is the main artery for wherever you want to travel. And, the view is getting better and better. Pass Road, which runs parallel to Beach Boulevard, handles much of the commuter traffic in the largest two Coast cities, Biloxi and Gulfport.
To bring you here, there's a really nice airport with a growing number of airlines servicing it. We're not talking local or regional. We're talking the Gulfport/Biloxi International Airport.
And once here, commuter buses and taxies can get you where you want to go, but if you plan a high-end night of casino hopping, rent a limousine for more stylish wheels.