Jacobi Boykins was 6 of 10 from 3-point range with 20 points on Saturday night and Louisiana Tech used a big first half to get past Southern Miss 89-66.
Amorie Archibald added 14 points and a career-high-tying 10 assists for the Bulldogs (13-9, 4-5 Conference USA), who led 57-27 at halftime.
Louisiana Tech never trailed and had a 26-4 run to build its largest lead at 49-18 late in the first half. The Golden Eagles (11-11, 4-5) got the deficit no closer than 21 in the second half.
Jy'lan Washington had 15 points and Oliver Powell added 10 for the Bulldogs.
Tyree Griffin led Southern Miss with 14 points and LaDavius Draine added 12.
Louisiana Tech made 11 of 18 from 3-point range and 21 of 30 overall in the first half.