Jacobi Boykins was 6 of 10 from 3-point range with 20 points on Saturday night and Louisiana Tech used a big first half to get past Southern Miss 89-66.
Amorie Archibald added 14 points and a career-high-tying 10 assists for the Bulldogs (13-9, 4-5 Conference USA), who led 57-27 at halftime.
Louisiana Tech never trailed and had a 26-4 run to build its largest lead at 49-18 late in the first half. The Golden Eagles (11-11, 4-5) got the deficit no closer than 21 in the second half.
Jy'lan Washington had 15 points and Oliver Powell added 10 for the Bulldogs.
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Tyree Griffin led Southern Miss with 14 points and LaDavius Draine added 12.
Louisiana Tech made 11 of 18 from 3-point range and 21 of 30 overall in the first half.