In a change from its previous recommendation, the U.S. Preventive Services Task Force now recommends that adults age 50 to 75 be screened for colorectal cancer using annual high-sensitivity fecal occult blood testing, sigmoidoscopy every five years with fecal occult testing between sigmoidoscopic exams, or colonoscopy every 10 years. According to the Task Force, good evidence exists that using these methods save lives. The recommendation and the accompanying summary of evidence is posted in the Annals of Internal Medicine online at www.annals.org and will appear in the Nov. 4 print edition of the journal.